- Placenta developed from union of chorionic frondosum and decidua basalis.
- It start to develop at 6week and complete at 12 week of pregnancy.
- Till 12 week of pregnancy the functions of providing nutrients to fetus is done by corpus luteum.
Placenta at Term-
- Shape- Circular dics Diameter- 15 to 20cm
- Thickness-3cm (at center) Weight- About 500gm
- Weight ratio of placenta with fetus:- 1:6 Occupies 30% part of uterine wall
STRUCTURE OF PLACENTA-
- Placenta consist of 2 plates, inner called basal plate and outer called chorionic plate.
- These plates also known as surface of placenta the basal plate is called Meternal surface,and chorionic plate is called as Fetal surface.
- Meternal surface-
- It is rough and spoagy surface, which is dark red in color.
- Grayish spots are seen due to calcium deposition.
- It is less than 1/5 part of total placenta.
- It has a shiny appearance due to the amnion covering of it.
- Umblical cord is present at its center.
- Branches of umbilical vessels are visible.
- It is 4/5 of total placenta.
- Space between plates are called " Intervillious space",which contain stem villi and its branches.
- Intervillious spaces also filled by slow flowing of meternal blood.
- Stem villi originate from chorionic plate and extend toward basal plate.
- Stem villi from primary, secondary and tertiary villi according their progressive development.
- Human placenta contain about 60 villi.
- Villi are functional unit of placenta, because villi are responsible for exchange between meternal and fetal blood.
- Few villi cause anchoring of placenta to decidua and some provide nutrition to fetus.
FUNCTION OF PLACENTA-
- Excretory function-
- Excretion of waste products like urea,uric acid, and creatinine from fetal circulation to meternal circulation by simple diffusion
- fetus required oxygen supply at the rate of 8ml/kg/minute from eternal circulation because there are no gases exchanges during fetal life by immature lungs, and this amount of oxygen is achieved by 165 to 135 ml/min cord blood flow.
- Transfer of gases assisted by slight maternal respiratory alkosis and fetal hemoglobin's high level and high affinity to oxygen.
3. Nutritive function-
- Fetus gets nutrients ( glucose, triglycerides and fatty acid, amino acid, water & electrolytes and hormones) from maternal blood by placenta. https://amzn.to/3mrMqH9
4. Barrier function-
- Placenta inhibited entry of harmful substance from maternal circulation to fetus e.g. maternal drugs and infection like rubella, chicken pox, polio, measles, mumps and bacterial.
- Some viruses like HIV and hepatitis can cross placental barriers.
- Immunoglobulins also passes from mother to fetus in the late in late pregnancy, which provide passive natural immunity to fetus for first 6 to 12 weeks.
5. Immunological function-
- Immunosuppressive effect by steroid hormones and HCG.
- Prevent fetal rejection by making blocking antibodies.
- Prevent deep penetration by decidual natural killer cells.
6. Endocrine function-
- It produces protein hormones like hCG, human placental lactogen(HPL), which also called human chorionic somatomammotropin (HCS), human placental growth harmone (hPGH) and insulin growth factor.
- It also produces steroid hormones like and estrogen and progesterone during pregnancy.
7. Storage function-
- It stores glycogen, iron and fat-soluble vitamins.